Premium Peptides for Advanced Laboratory Research
When conducting precise in-vitro studies, the purity of your compounds is critical. GenX Peptides offers PE-22-28 synthesized to the highest industry standards.
This specific sequence ensures reliable, reproducible data. It is ideal for investigating neurological signaling and potassium channel regulation in your laboratory.
What is PE-22-28?
This formulation is a synthetically engineered peptide derived from Spadin, a natural peptide cleaved from the sortilin protein. The PE-22-28 structure acts as a highly specific antagonist of the TREK-1 potassium channel in the central nervous system.
Its baseline structural characteristics and chemical parameters are cataloged extensively in PubChem’s compound database.
In tissue cultures, researchers utilize this compound to observe its regulatory effects on neurogenesis and synaptic plasticity. By blocking the TREK-1 channel, it alters neuronal excitability and stimulates specific intracellular signaling cascades.
This specific mechanism and its resulting intracellular interactions, particularly regarding brain-derived neurotrophic factor (BDNF) expression, are widely reviewed in National Institutes of Health (NIH) literature. It provides highly valuable data when studying mood regulation and neuroprotection models in isolated environments.
Key Research Applications
The scientific community utilizes this synthetic Spadin derivative heavily in neurobiological research. Current laboratory applications for PE-22-28 include:
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TREK-1 Inhibition: Observing how the sequence binds to and blocks specific background potassium channels in isolated cell cultures.
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Neurogenesis Analysis: Investigating mechanisms of neuronal proliferation and synaptic remodeling in in-vitro models.
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BDNF Expression Tracking: Researching how the formulation influences neurotrophic factor upregulation and cellular survival parameters.
Storage and Reconstitution
Proper handling is required to maintain the structural integrity of your PE-22-28. The product ships as a stable lyophilized powder.
Store vials away from direct light and heat. Once reconstituted with an appropriate laboratory solvent, refrigerate between 2°C and 8°C.
Handle the solution with care to prevent the degradation of the delicate peptide chains.
Why Choose GenX Peptides?
We prioritize the integrity of your research above all else. Operating as a premier USA-based supplier, we ensure every batch undergoes rigorous high-performance liquid chromatography (HPLC) and mass spectrometry testing.
This strict quality control allows us to guarantee a purity level exceeding 99%.
Disclaimer: All products listed on GenX Peptides are sold exclusively for scientific research and laboratory use. They are not intended for human or animal consumption.
